Analysis of the physical properties of incorporating cannabis oil in products for the control of alveolitis

Résumé

This study evaluated the incorporation of Cannabis sativa oil into dental formulations designed for the management of alveolitis, a common postoperative complication characterized by severe pain and inflammation following tooth extraction. The aim was to determine whether cannabis oil, modifies essential physical properties compared with eugenol, traditionally used in alveolitis dressings. Two experimental groups were prepared, both combined with tetracycline: one with full-spectrum cannabis oil and the other with eugenol. The materials were subjected to standardized flow, radiopacity, and solubility tests according to ISO guidelines. Flow was measured using standardized discs; radiopacity was assessed by occlusal radiographs with an aluminum step wedge; and solubility was tested using Teflon molds under controlled temperature and humidity conditions. The results demonstrated that the association of tetracycline and cannabis oil exhibited significantly greater flow than the tetracycline-eugenol group, indicating improved adaptability of the material to the alveolar socket. Radiopacity analysis revealed no statistical difference between groups, remaining within clinically acceptable ranges. The solubility test could not be completed, since both materials failed to set under the experimental conditions. It is concluded that replacing eugenol with cannabis oil in dental formulations did not compromise radiopacity and provided superior flow, a desirable characteristic for clinical adaptation. These findings suggest that Cannabis sativa oil formulations may represent a promising alternative for alveolitis management. However, further studies on biocompatibility, antimicrobial activity, and clinical efficacy are required to confirm its applicability in routine dental practice.  

Keywords: Cannabis sativa, cannabinoids, CBD, pain management, inflammation.